The changing faces of glutathione, a cellular protagonist. The result of hematology indices is presented in Table3. McCune LM, Johns T. Antioxidant activity in medicinal plants associated with the symptoms of diabetes mellitus used by the indigenous peoples of the north American boreal forest. While histology of organs showed no adverse pathological lesions in the internal organs of rats, higher dose (1200mg/kg) over a period of time could cause noticeable liver and kidney injury. The renal cortex showed normal glomeruli with mesangial cells and capsular spaces appeared normal (white arrow), the renal tubules appear normal (blue arrow) and interstitial spaces also observed normal (black arrow). Note: A=change in absorbance, TV=total volume, SV=sample volume, =molar extinction=4020M1cm1, TP=total protein. Mr. T.S. 2010;4(8):6804 https://doi.org/10.5897/JMPR09.487. Consequently, the effects of the extract on MDA level could indicate damage to cell membrane lipids of the hepatocyte which could result to increased generation of reactive oxygen species (ROS). This information may not fit your specific health circumstances. Badami S, Aneesh R, Sankar S, Sathishkumar MN, Suresh B, Rajan S. Antifertility activity of Derris brevipes variety coriacea. CAS 2012;9(1):817 https://doi.org/10.4314/ajtcam.v9i1.12. The animals were allowed free access to rat chow and water ad libitum. The liver and kidney of rats administered with 500mg/kg JCEE and above demonstrated slight increase in MDA level with significant (P<0.05) increase only observed in the liver of rats that received 1200mg/kg of extract. Create a membership account to save your garden designs and to view them on any device. Compared to the control, total protein in liver and kidney were statistically not altered except rats that were administered with 1200mg/kg JCEE that showed significant (p<0.05) decrease in the liver. Mr. K.O. Studies have shown that ewe eje contains antioxidant and cardio-protective properties. By entering your email address you agree to receive a daily email newsletter from Plant Care Today. The liver and kidneys excised from all the experimental rats were fixed in a labeled sample bottles containing 10% formalin and processed for histological examination. Pot the specimen and bring it indoors to add a bright touch of color to your interiors. It creates the perfect environment for aphids and dried sod. 1978;90:819. Studies on The Phytochemical and Nutritional CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Consumption of medicinal plants without scrutinizing its efficacy and safety can result in unexpected toxic effects resulting in physiology changes of different organs in the body. This is attributed to the anti-hyperlipidaemic properties of the plant. Use liquid fertilizers, slow-release or granulated formulas. CAS long (20 cm), densely packed with pink to crimson tubular flowers. It also can be used in combination with other vegetables such as the Efinrin (scent leaves), ugwu etc. 2015;6(7):265270. The reaction is terminated by the addition of 2ml of dichromoacetic acid mixture (potassium dichromate (5%) and glacial acetic acid; 1:3v/v) and heated at 60C for 10min. It helps in replenishing blood lost during period. Over time, they cause atherosclerosis and myocardia infarction. Correspondence to White blood cell counts usually increases following foreign invaders (pathogens) resulting in normal body physiological response which boost the bodys defense mechanisms [28, 29]. In these groups, from mild to severe order; shows observable congested portal vein, the liver parenchyma showed area of harmorrhage, the morphology of the hepatocytes appear pyknotic, some show mild fat infiltration (red arrow) the sinusoids appear fibrotic with infiltration of inflammatory red cells (red arrow). A total number of forty two (42) male albino rats weighing between 120 and 170g were used in this study. Hence, the use of Justicia carnea leaves may help reduce your risk of heart diseases, heart attack, stroke etc. PubMedGoogle Scholar. Niger J Physiol Sci. Justicia Carnea leaves extract contains a rich supply of iron, riboflavin, vitamins A, C, E, B1, B2, B9, and B12. Ogwu obara is commonly used in making porridge yam, and soups. J Am Diet Assoc. The animals were randomly distributed into cages and allowed to acclimatize for 2 weeks in a well ventilated room under natural lighting condition. Contamination of medicinal plant could be as a result of contaminants (such as heavy metals, aflatoxin and pathogenic microbes) from soil and manner of herbal preparations [4]. Histopathological examination of liver and kidney showed mild to severe pathological lesion in a dose dependent manner. 16. Background: Justicia carnea is a medicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. Further study assessing the kidney indices (urea, creatinine and electrolytes) is however encouraged to ascertain the safety of the plant extract on renal function. 400). Extraction was carried out by maceration (72h) following the method of Onoagbe et al., [13]. International Journal of Phytomedicine and Phytotherapy, Clinical Phytoscience Effect of the ethanol extract of Justicia carnea leaves on the red All authors read and approved the final draft of the manuscript. van Andel T., Carvalheiro LG. Note this is the default cart. The fresh leaves were thoroughly washed under running tap, air dried under shade, pulverized and extracted with ethanol. This suggested that the extract did not alter tissue function in converting harmful hydrogen peroxide to water and oxygen. Despite the therapeutic importance of medicinal plants, toxic substances have been shown to be present in large numbers of plants investigated [3]. Join now and start creating your dream garden! The description of these plants has been written based on numerous outside resources. It is also known as Jacobinia carnea, and is a part of the Acanthaceae family along with the Aphelandra squarrosa (Zebra plant) and Crossandra. Kone WM, Koffi AG, Bomisso EL, Tra Bi FH. Methods. Privacy Chanda S, Parekh J, Vaghasiya Y, Dave R, Baravalia Y, Nair R. Medicinal plants - from traditional use to toxicity assessment: a review. Aside boosting blood production in normal persons, justicia carnea leaves also reverses anemic conditions. When you boil the plant, it turns the water red. Leal, L. K., Ferreira, A. 2. ESA conceived and designed the study. Generally disease free. 1.3.1 Aetiologyof Anaemia Anaemia may be due to a single factor such as a nutritional deficiency or multifactorial (McEvoy, 2013). Studies on The Phytochemical and Nutritional Composition of Aqueous It is commonly referred to as blood root, blood booster, ewe eje in Yoruba, Ogwu obara in Igbo, and jacobinia in Brazil and south America. From mild to severe order, the graded doses showed distorted renal cortex with collapsed renal glomeruli and dillated capsular spaces. Medapa S, Singh GRJ, Ravikumar V. The phytochemical and antioxidant screening of Justicia wynaadensis. Keep in mind that natural products are not always necessarily safe and dosages can be important. In winter, you might have to spray the leaves with water, especially if the air is dry. 32 years old (Greco et al., 1974), long-term treatment side effects are becoming more critical. J. Appl. African J Plant Sci. All rights reserved. Luckily, the unique flowers of Jacobinia carnea and its foliage are free from major pest and disease concerns. -Amylase binding-interaction with JCAE was also investigated using fluorescence spectroscopy and molecular docking. Ethnomedical study and iron content of some medicinal herbs used in traditional medicine in cote divoire for the treatment of anaemia. National Research Council. The compound responsible for this activity is lignan. 2019;30(4):64554. One of the symptoms of diabetes is elevated blood glucose level.
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